Cadila pharmaceuticals trigan d skin#

Adrenostimulants, as well as other drugs with an anticholinergic effect, increase the risk of side effects. Ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, which makes it possible to develop severe intoxications with small overdoses of paracetamol. Stimulators of microsomal oxidation in the liver (phenytoin. Interaction with other drugsДЄmantadine, class I antiarrhythmic drugs, antipsychotics, benzodiazepines, MAO inhibitors, narcotic analgesics, nitrates and nitrites, sympathomimetic drugs, tricyclic antidepressants enhance the action of dicycloverin.Дicycloverin increases the concentration of dioxin in the blood (due to slower gastric emptying). peptic ulcer of the stomach and duodenum (phase of exacerbation) Д¬aution should be used in patients with severe impaired liver or kidney function, with a genetic absence of glucose-6-phosphate dehydrogenase, blood disease, glaucoma, benign hyperbilirubinemia (including Gilbert syndrome), viral hepatitis, alcoholic liver damage, alcoholism, in old age. Hypersensitivity to paracetamol and dicycloverine On the part of the organs of vision: mydriasis, blurred visual perception, paralysis of accommodation, increased extraocular pressure. Hematopoietic organs: anemia, methemoglobinemia (cyanosis, shortness of breath, heart pain), hemolytic anemia (especially for patients with gluco-6-phosphate dehydrogenase deficiency).ДЇrom the genitourinary system: pyuria, urinary retention, interstitial nephritis, papillary necrosis. Sides of the central nervous system (usually develops when taking high doses): drowsiness, dizziness, psychomotor agitation and disorientation.ДЇrom the endocrine system: hypoglycemia, up to hypoglycemic coma.

Cadila pharmaceuticals trigan d skin#

Side effectsДЇrom the gastrointestinal tract: dry mouth, loss of taste, loss of appetite, epigastric pain, constipation, increased activity of liver enzymes, usually without the development of jaundice, hepatonecrosis (dose-dependent effect).ДЄllergic reactions: skin rash, itching, urticaria, Quincke's edema, erythema multiforme exudative (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome). With prolonged use of the drug, it is necessary to control the picture of peripheral blood and the functional state of the liver.Дo not exceed the daily dose its increase or longer treatment is possible only under the supervision of a doctor, because an overdose of the drug can cause liver failure. The duration of admission without consulting a doctor is no more than 5 days when prescribed as an anesthetic and 3 days as an antipyretic. The maximum single dose for adults is 2 tablets, daily 4 tablets. It is used internally for adults and children over 15 years old by 1 tab. Infectious and inflammatory diseases accompanied by fever. spasm of smooth muscles of internal organs The combined action of the two components of Trigan-D provides relaxation of the spasmodic smooth muscles of the internal organs and the weakening of pain. In therapeutic doses, it causes effective relaxation of smooth muscles, which is not accompanied by side effects characteristic of atropine. The second component of dicycloverin hydrochloride is a tertiary amine, which has a relatively weak non-selective m-anticholinergic and direct myotropic antispasmodic effect on the smooth muscles of internal organs.

The mechanism of action is associated with moderate inhibition of cyclooxygenase-1 and, to a lesser extent, cyclooxygenase-2 in peripheral tissues and the central nervous system, resulting in inhibition of prostaglandin biosynthesis of pain modulators, thermoregulation, and inflammation. Paracetamol, which is part of the drug, has an analgesic, antipyretic and minor anti-inflammatory effect. Duration of admission? no more than 5 days. Maximum single dose? 2 tablets, daily? 4 tab. Pharmacological action - antispasmodic, analgesic.